Biomimetic honeycomb-patterned surface as the tunable cell adhesion scaffold.

Supporting Information Biomimetic Honeycomb-patterned Surface as the Tunable Cell Adhesion Scaffold

Manufacturing a Biomimetic Biorecator in Cardiac Tissue Engineering

Introduction: The direct approach of cardiac tissue engineering is to mimic the natural tissue of heart, considering the significant role of scaffolding and mechanical simulation.  Methods: To achieve this purpose, a composite Polycaprolactone (PCL)/Gelatin electrospun scaffold with a ratio of 70:30 and with the most similarities to the cardiac extracellular matrix was fabricated with aligned ...

Biomimetic modification of porous TiNbZr alloy scaffold for bone tissue engineering.

Porous titanium (Ti) and Ti alloys are important scaffold materials for bone tissue engineering. In the present study, a new type of porous Ti alloy scaffold with biocompatible alloying elements, that is, niobium (Nb) and zirconium (Zr), was prepared by a space-holder sintering method. This porous TiNbZr scaffold with a porosity of 69% exhibits a mechanical strength of 67 MPa and an elastic mod...

Enhanced Neural Cell Adhesion and Neurite Outgrowth on Graphene-Based Biomimetic Substrates

Neural cell adhesion and neurite outgrowth were examined on graphene-based biomimetic substrates. The biocompatibility of carbon nanomaterials such as graphene and carbon nanotubes (CNTs), that is, single-walled and multiwalled CNTs, against pheochromocytoma-derived PC-12 neural cells was also evaluated by quantifying metabolic activity (with WST-8 assay), intracellular oxidative stress (with R...

Independent tuning of multiple biomaterial properties using protein engineering†

A key attribute missing from many current biomaterials is the ability to independently tune multiple biomaterial properties without simultaneously affecting other material parameters. Because cells are well known to respond to changes in the initial elastic modulus, degradation rate, and cell adhesivity of a biomaterial, it is critical to develop synthetic design strategies that allow decoupled...